| 000 | 03522nlm1a2200493 4500 | ||
|---|---|---|---|
| 001 | 667899 | ||
| 005 | 20231030042130.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\39110 | ||
| 035 | _aRU\TPU\network\35830 | ||
| 090 | _a667899 | ||
| 100 | _a20220513a2022 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aElectrospun composites of poly-3-hydroxybutyrate reinforced with conductive fillers for in vivo bone regeneration _fR. A. Surmenev, A. N. Ivanov, A. Cecilia [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 47 tit.] | ||
| 330 | _aThe aim of this study was to investigate the biocompatibility and osteoinductive properties of fibrous scaffolds implanted in the bone tissue of white rats in vivo. The effect of various concentrations of conductive PANi (2 and 3 wt%) and rGO (0.2 and 1 wt%) in the PHB scaffolds on the reparative processes of bone callus formation in white rats was studied. On the 28th day after implantation, a histomorphological study of the preparations of the transverse section of the diaphysis of the femur of the implantation area was performed. The results of implantation tests in the femur revealed that all the studied scaffolds are biocompatible and the most pronounced stimulating effect on bone formation was observed for hybrid PHB scaffolds doped with 3 wt% PANi and 0.2 wt% rGO compared with pure PHB scaffolds, thus determining further prospects to study the osteoinductive features of hybrid PHB scaffolds. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tOpen Ceramics | ||
| 463 |
_tVol. 9 _v[100237, 9 p.] _d2022 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _abiodegradable scaffolds | |
| 610 | 1 | _apoly-3-hydroxybutyrate | |
| 610 | 1 | _aosteoinductivity | |
| 610 | 1 | _aelectrospinning | |
| 610 | 1 | _ain vivo study | |
| 610 | 1 | _aбиоразлагаемые материалы | |
| 610 | 1 | _aостеоиндуктивные покрытия | |
| 610 | 1 | _aэлектропрядение | |
| 701 | 1 |
_aSurmenev _bR. A. _cphysicist _cAssociate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences _f1982- _gRoman Anatolievich _2stltpush _3(RuTPU)RU\TPU\pers\31885 |
|
| 701 | 1 |
_aIvanov _bA. N. _gAleksey |
|
| 701 | 1 |
_aCecilia _bA. _gAngelica |
|
| 701 | 1 |
_aBaumbach _bT. _gTilo |
|
| 701 | 1 |
_aChernozem _bR. V. _cphysicist _claboratory assistant of Tomsk Polytechnic University _f1992- _gRoman Viktorovich _2stltpush _3(RuTPU)RU\TPU\pers\36450 |
|
| 701 | 1 |
_aMathur _bS. _gSanjay |
|
| 701 | 1 |
_aSurmeneva _bM. A. _cspecialist in the field of material science _cengineer-researcher of Tomsk Polytechnic University, Associate Scientist _f1984- _gMaria Alexandrovna _2stltpush _3(RuTPU)RU\TPU\pers\31894 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _bНаучно-исследовательский центр "Физическое материаловедение и композитные материалы" _h8209 _2stltpush _3(RuTPU)RU\TPU\col\24957 |
| 801 | 2 |
_aRU _b63413507 _c20220513 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1016/j.oceram.2022.100237 | |
| 942 | _cCF | ||