| 000 | 05121nlm1a2200529 4500 | ||
|---|---|---|---|
| 001 | 668014 | ||
| 005 | 20231030042134.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\39225 | ||
| 035 | _aRU\TPU\network\39034 | ||
| 090 | _a668014 | ||
| 100 | _a20220527a2022 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aCore-Shell Magnetoactive PHB/Gelatin/Magnetite Composite Electrospun Scaffolds for Biomedical Applications _fA. Pryadko, V. V. Botvin, Yu. R. Mukhortova [et al.] |
|
| 203 |
_aText _celectronic |
||
| 320 | _a[References: 75 tit.] | ||
| 330 | _aNovel hybrid magnetoactive composite scaffolds based on poly(3-hydroxybutyrate) (PHB), gelatin, and magnetite (Fe3O4) were fabricated by electrospinning. The morphology, structure, phase composition, and magnetic properties of composite scaffolds were studied. Fabrication procedures of PHB/gelatin and PHB/gelatin/Fe3O4 scaffolds resulted in the formation of both core-shell and ribbon-shaped structure of the fibers. In case of hybrid PHB/gelatin/Fe3O4 scaffolds submicron-sized Fe3O4 particles were observed in the surface layers of the fibers. The X-ray photoelectron spectroscopy results allowed the presence of gelatin on the fiber surface (N/C ratio–0.11) to be revealed. Incubation of the composite scaffolds in saline for 3 h decreased the amount of gelatin on the surface by more than ~75%. The differential scanning calorimetry results obtained for pure PHB scaffolds revealed a characteristic melting peak at 177.5 °C. The presence of gelatin in PHB/gelatin and PHB/gelatin/Fe3O4 scaffolds resulted in the decrease in melting temperature to 168–169 °C in comparison with pure PHB scaffolds due to the core-shell structure of the fibers. Hybrid scaffolds also demonstrated a decrease in crystallinity from 52.3% (PHB) to 16.9% (PHB/gelatin) and 9.2% (PHB/gelatin/Fe3O4). All the prepared scaffolds were non-toxic and saturation magnetization of the composite scaffolds with magnetite was 3.27 ± 0.22 emu/g, which makes them prospective candidates for usage in biomedical applications. | ||
| 461 | _tPolymers | ||
| 463 |
_tVol. 14, iss. 3 _v[529, 17 p. ] _d2022 |
||
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _amagnetoactive scaffold | |
| 610 | 1 | _apoly-3-hydroxybutyrate | |
| 610 | 1 | _amagnetite | |
| 610 | 1 | _acomposite | |
| 610 | 1 | _acore-shell structure | |
| 610 | 1 | _aмагнетит | |
| 610 | 1 | _aструктура | |
| 701 | 1 |
_aPryadko _bA. _cSpecialist in the field of nuclear technologies _cResearch Engineer of Tomsk Polytechnic University _f1995- _gArtyom _2stltpush _3(RuTPU)RU\TPU\pers\46948 |
|
| 701 | 1 |
_aBotvin _bV. V. _cchemist _cSenior Researcher of Tomsk Polytechnic University, Candidate of chemical sciences _f1991- _gVladimir Viktorovich _2stltpush _3(RuTPU)RU\TPU\pers\47211 |
|
| 701 | 1 |
_aMukhortova _bYu. R. _cChemical engineer _cEngineer of Tomsk Polytechnic University _f1976- _gYulia Ruslanovna _2stltpush _3(RuTPU)RU\TPU\pers\46606 |
|
| 701 | 1 |
_aPary (Pariy) _bI. O. _cphysicist _cengineer of Tomsk Polytechnic University _f1995- _gIgor Olegovich _2stltpush _3(RuTPU)RU\TPU\pers\45219 |
|
| 701 | 1 |
_aVagner _bD. V. _gDmitry Viktorovich |
|
| 701 | 1 |
_aLaktionov _bP. P. _gPavel Petrovich |
|
| 701 | 1 |
_aChernonosova _bV. S. _gVera Sergeevna |
|
| 701 | 1 |
_aChelobanov _bB. P. _gBoris Pavlovich |
|
| 701 | 1 |
_aChernozem _bR. V. _cphysicist _claboratory assistant of Tomsk Polytechnic University _f1992- _gRoman Viktorovich _2stltpush _3(RuTPU)RU\TPU\pers\36450 |
|
| 701 | 1 |
_aSurmeneva _bM. A. _cspecialist in the field of material science _cengineer-researcher of Tomsk Polytechnic University, Associate Scientist _f1984- _gMaria Alexandrovna _2stltpush _3(RuTPU)RU\TPU\pers\31894 |
|
| 701 | 1 |
_aKholkin _bA. L. _cphysicist _cDirector of the International Research Center for PMEM of the Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences _f1954- _gAndrei Leonidovich _2stltpush _3(RuTPU)RU\TPU\pers\47207 |
|
| 701 | 1 |
_aSurmenev _bR. A. _cphysicist _cAssociate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences _f1982- _gRoman Anatolievich _2stltpush _3(RuTPU)RU\TPU\pers\31885 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _bНаучно-исследовательский центр "Физическое материаловедение и композитные материалы" _h8209 _2stltpush _3(RuTPU)RU\TPU\col\24957 |
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20220527 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.3390/polym14030529 | |
| 942 | _cCF | ||