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100 _a20230125a2022 k y0engy50 ba
101 0 _aeng
102 _aGB
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181 0 _ai
182 0 _ab
200 1 _aElectrochemical Sensors for the Detection of Reactive Oxygen Species in Biological Systems: A Critical Review
_fA. V. Geraskevich, A. N. Solomonenko, E. V. Dorozhko [et al.]
203 _aText
_celectronic
300 _aTitle screen
330 _aReactive oxygen species (ROS) involving superoxide anion, hydrogen peroxide and hydroxyl radical play important role in human health. ROS are known to be the markers of oxidative stress associated with different pathologies including neurodegenerative and cardiovascular diseases, as well as cancer. Accordingly, ROS level detection in biological systems is an essential problem for biomedical and analytical research. Electrochemical methods seem to have promising prospects in ROS determination due to their high sensitivity, rapidity, and simple equipment. This review demonstrates application of modern electrochemical sensors for ROS detection in biological objects (e.g., cell lines and body fluids) over a decade between 2011 and 2021. Particular attention is paid to sensors materials and various types of modifiers for ROS selective detection. Moreover, the sensors comparative characteristics, their main advantages, disadvantages and their possibilities and limitations are discussed.
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 _tCritical Reviews in Analytical Chemistry
463 _tVol. X, iss. X
_v[33 p.]
_d2022
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _abiological objects
610 1 _abody fluid
610 1 _acell
610 1 _aelectrochemical sensor
610 1 _areactive oxygen species
610 1 _aбиологические объекты
610 1 _aжидкости
610 1 _aорганизмы
610 1 _aклетки
610 1 _aэлектрохимические датчики
610 1 _aактивные формы
610 1 _aкислород
701 1 _aGeraskevich
_bA. V.
_cchemical technologist
_cengineer of Tomsk Polytechnic University
_f1997-
_gAlina Vadimovna
_2stltpush
_3(RuTPU)RU\TPU\pers\46993
701 1 _aSolomonenko
_bA. N.
_cChemical engineer
_cEngineer of Tomsk Polytechnic University
_f1995-
_gAnna Nikolaevna
_2stltpush
_3(RuTPU)RU\TPU\pers\47012
701 1 _aDorozhko
_bE. V.
_cchemist
_cEngineer of Tomsk Polytechnic University
_f1979-
_gElena Vladimirovna
_2stltpush
_3(RuTPU)RU\TPU\pers\32174
701 1 _aKorotkova
_bE. I.
_cchemist
_cProfessor of Tomsk Polytechnic University, Doctor of chemical science
_f1965-
_gElena Ivanovna
_2stltpush
_3(RuTPU)RU\TPU\pers\31278
701 1 _aBarek
_bJ.
_gJiri
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИнженерная школа природных ресурсов
_bОтделение химической инженерии
_h8085
_2stltpush
_3(RuTPU)RU\TPU\col\23513
801 2 _aRU
_b63413507
_c20230125
_gRCR
856 4 _uhttps://doi.org/10.1080/10408347.2022.2098669
942 _cCF