| 000 | 03123nlm1a2200409 4500 | ||
|---|---|---|---|
| 001 | 669357 | ||
| 005 | 20231030042220.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\40597 | ||
| 035 | _aRU\TPU\network\15276 | ||
| 090 | _a669357 | ||
| 100 | _a20230329d2023 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aGB | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aLigand-free Ullmann-type arylation of oxazolidinones by diaryliodonium salts _fE. V. Podrezova, A. A. Okhina, A. D. Rogachev [et al.] |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 330 | _aThe arylation of azaheterocycles can be considered as one of the most important processes for the preparation of various biologically active compounds. In the present work, we describe a method for the copper-catalyzed N-arylation of hindered oxazolidinones using diaryliodonium salts. The method succeeds in good to excellent yields for the arylation of 4-alkyloxazolidinones, including sterically hindered isopropyl- and tert-butyl-substituted. The efficiency of the method was demonstrated for a wide range of diaryliodonium salts – symmetric and unsymmetric as well as ortho-substituted derivatives. The developed approach will provide an important contribution in the development and preparation of novel drugs and bioactive molecules containing oxazolidinone moieties. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tOrganic and Biomolecular Chemistry | ||
| 463 |
_tVol. 21, iss, 9 _v[P. 1952-1957] _d2023 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 701 | 1 |
_aPodrezova _bE. V. _cChemist _cEngineer of Tomsk Polytechnic University _f1992- _gEkaterina Vladimirovna _2stltpush _3(RuTPU)RU\TPU\pers\40301 |
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| 701 | 1 |
_aOkhina _bA. A. _gAlina Aleksandrovna |
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| 701 | 1 |
_aRogachev _bA. D. _gArtem Dmitrievich |
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| 701 | 1 |
_aBaykov _bS. V. _cchemist _cResearcher at Tomsk Polytechnic University, Candidate of Chemical Sciences _f1987- _gSergey Valentinovich _2stltpush _3(RuTPU)RU\TPU\pers\47276 |
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| 701 | 1 |
_aKirschning _bA. _gAndreas |
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| 701 | 1 |
_aYusubov _bM. S. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of chemical sciences _f1961- _gMekhman Suleiman-Ogly (Suleimanovich) _2stltpush _3(RuTPU)RU\TPU\pers\31833 |
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| 701 | 1 |
_aSoldatova _bN. S. _corganic chemist _cengineer of Tomsk Polytechnic University _f1992- _gNataliya Sergeevna _2stltpush _3(RuTPU)RU\TPU\pers\36289 |
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| 701 | 1 |
_aPostnikov _bP. S. _corganic chemist _cAssociate Professor of Tomsk Polytechnic University, Candidate of chemical sciences _f1984- _gPavel Sergeevich _2stltpush _3(RuTPU)RU\TPU\pers\31287 |
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| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20230329 _gRCR |
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| 856 | 4 | _uhttps://doi.org/10.1039/D2OB02122F | |
| 942 | _cCF | ||